Main Features:
7. The equipment of production and inspection should have records of use and maintenance, and be managed by special personnel.
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As the world's largest mattress manufacturer, Simmons filed for bankruptcy protection, it revealed a very dangerous signal: the US economy is likely to fall into a second wave of recession. The United States is the most diligent country in the world to replace soft mattresses. The speed of changing mattresses is faster than that of Chinese people changing phones.
But the financial tsunami that has not happened in a hundred years has plunged the US economy. Americans are becoming more and more unintentional, and mattresses have become the most durable consumer goods. This led to the stagnation of sales of Simmons, which has a history of 100 years, and its performance has fallen sharply, and it has to seek bankruptcy protection.
At present, the mattress index has become an important indicator for economists to observe the economic boom: when the economy is booming, people are happy, frequent things, natural sales of soft mattresses are booming, and when the economy is depressed, things are not smooth, poor couples are sorrowful, cattle The clothes were so weeping, the mind was not in bed, and the sales of mattresses naturally fell.
People are born in Sri Lanka, loves to die, and die in Sri Lanka. People spend more than a third of their lives in bed.
Simmons is actually a symbol of the American way of life. Zalmon Gilbert Simmons is the inventor of the world's first soft spring mattress. When people all over the world are still sleeping on hardwood beds, Mr. Simmons, the well-known American entrepreneur, began to think hard about how to let himself sleep. Better. So he developed the world's first soft spring mattress. The American life has entered the "lathe era", the Americans in Hollywood movies are not in the car, or in the bed. "Open your eyes and drive the car to the world, and close your eyes and sleep on the Simmons bed."
The first sleeping mattress in China was the Empress Dowager Cixi. At that time, only these noble bodies could afford to sleep in expensive Simmons.
In 1935, Simmons entered the Chinese market for the first time and made a comeback in a few decades. Today, mainland China has become the best overseas market for Simmons.
But Simmons can't keep up in the United States.
What Americans are most afraid of is that their way of life has been changed: if the Chinese are sleeping on Simmons and letting Americans sleep on hard beds, then they are the end. But a financial tsunami has indeed changed the way Americans live. They began to carefully save money, the American household savings rate rose from minus 5% to plus 12%; the speed at which Americans changed mattresses was greatly slowed down, and it was difficult to find 70% new Simmons mattresses on the dump. .
Therefore, from the bankruptcy of Simmons, we deeply understand that the impact of the global financial crisis is far from over.
It meets national relative standards, according to GMP and implementation guidelines of GMP, AND gb/t522 6.1-1996
2. The surface of equipment directly in contact with drug is easy to clean, smooth, easy to clean or sterilize, and resistant to corrosion, and chemical changes or adsorption of drugs will not occur. Lubricants, coolants, etc. used in the equipment can not cause contamination of the medicines or containers.
3. The main fixed pipeline connected to the equipment shall indicate the name and direction of the material.
4. The preparation, storage and distribution of purified water and water for injection should prevent the growth and contamination of microorganisms. The materials used for storage tanks and pipelines should be non-toxic and corrosion-resistant. The design and installation of the pipeline should avoid dead ends and blind pipes. Storage tanks and pipelines are required to provide cleaning and sterilization cycles. The vent of injection water tank should be equipped with a hydrophobic sterilizing filter that does not come off the fibers. The water for injection can be stored at a temperature above 80°C, at a temperature above 65°C, or below 4°C.
5. Instruments, meters, gauges, scales, etc. used for production and inspection, whose scope of application and precision shall meet the inspection requirements of production, have obvious conformity marks, and be regularly calibrated.
6. Production equipment should have obvious status signs and be regularly repaired, maintained and verified. Equipment installation, and maintenance can not affect the quality of the product. Unqualified equipment should be moved out of the production area if possible, and should be clearly marked before being carried out.
According to an informed source from the Wall Street Journal, Simmons Co may file for bankruptcy protection under Chapter 11 of the Bankruptcy Law. According to the plan, the company will be sold to private equity firm Ares Management LLC and the Ontario Teachers' Pension Plan.