Excessive methionine

Methionine is an essential amino acid in the compound feed of laying hens. It has the function of promoting the growth and development of laying hens, increasing egg production rate, increasing feed compensation and increasing economic benefits. However, excessive addition of methionine can cause metabolic disorders in laying hens. A case of egg methionine poisoning that occurred in our county in 1997 is as follows: b4b China Feed Industry Information Network - based on feed, serving animal husbandry

1 Incidence situation: 1100 dika hens fed by a farmer have normal growth and development when feeding full-price feed, and have begun to lay eggs. Because he wanted to recover his investment as soon as possible, he purchased the high-yield feed of Hope Brand Chicken from Sichuan Luzhou Hope Feed Co., Ltd., and replaced the original laying chicken feed. At the same time, a certain amount of methionine is added, and it is desirable to reach the peak of egg production as soon as possible. After two weeks of feeding, he found that all the hens had increased their drinking water and did not increase their eggs. The weather was hot and it was thought to be hot. After another ten days, some chickens gradually reduced their feeding, increased drinking water, and decreased egg production. They began to produce small eggs, thin shell eggs, soft eggs, loose feathers and less light, oral flow, and apathetic. The medication did not improve, the condition worsened, and chickens began to die. B4b China Feed Industry Information Network - based on feed, serving animal husbandry

2 pathological anatomy: after dissection of the diseased chicken, the pathological changes were found to be the same, hepatomegaly, brittle and fragile, soil yellow; kidney enlargement, brittleness; intestinal thinning; cardiac steatosis; a small amount of pus in the cloaca; Slight inflammation, slightly enlarged tubal. B4b China Feed Industry Information Network - based on feed, serving animal husbandry

3 diagnosis and treatment measures: according to symptoms, changes in feed and anatomical pathological changes, the elimination of infectious diseases, diagnosed as methionine poisoning. Immediately stop feeding the original compound feed, supply clean drinking water with 5% glucose and 0.01% Vc; buy green and succulent vegetables such as cabbage leaves and kale, chopped and fed; feed once a day with 2% feed complex enzyme 2% licorice powder, 3% mung bean powder, self-matched methionine-free feed. After ten days, all the sick chickens gradually became normal, and the symptoms gradually disappeared. After 30 days, the eggs returned to normal and the feed was changed. After 37 days, the eggs reached a peak and they recovered completely without death. B4b China Feed Industry Information Network - based on feed, serving animal husbandry

4 Lessons learned: Methionine is an important amino acid in laying hens. Under normal circumstances, methionine is absorbed by the chicken body, and under the action of various amino acid enzymes, it is mainly decomposed, anabolized in the liver and kidney, and converted into protein, nitrogen-containing active substance and energy for the growth and development of the body. However, if the methionine in the feed is excessive, the amount of methionine absorbed into the liver exceeds the decomposition and synthesis ability of the liver. Normal decomposition and anabolism are destroyed, resulting in various toxic substances that cannot be decomposed and eliminated, accumulating in the liver and kidney, causing liver and kidney. The cells are denatured and enlarged, which causes the metabolic balance of the laying hens to be disordered and poisoning occurs. In general, the laying hen has enough methionine in the compound feed, no need to add it, and it is eager to encourage excessive addition, but it will be counterproductive. Therefore, to raise laying hens, do not blindly increase the methionine content in the feed. B4b China Feed Industry Information Network - based on feed, serving animal husbandry

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